I've had some problems with my hands recently. I developed a rather nasty callous on my middle finger with the constant rubbing of the scissors while I was cutting the fine applique.
More alarmingly I noticed the nerves in the same finger were being affected by constant use of the scissors. I had electric shocks playing riot in my hand at times.
I love my applique scissors, (I use 7" Dovo Scissors) but I realized that I needed to make some adjustments, so now armed with two new pairs of very expensive scissors with wider padded handles, I hope I can repair the damage.
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This sounds like the start of RSI, have you been to a doctor?
Maybe just a reaction to the metal, I find I get arthritic type pains if I use metal knitting needles but am fine with plastic or bamboo.